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TAVAS SAĞLIK HİZMETLERİ MESLEK YÜKSEKOKULU >> ECZANE HİZMETLERİ >> ECZANE HİZMETLERİ
YÖK AKADEMİK ORCID: 0000-0003-1534-8117Eğitim Bilgileri
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2013 - 2020 Doktora
ANADOLU ÜNİVERSİTESİ
SAĞLIK BİLİMLERİ ENSTİTÜSÜ
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2010 - 2013 Yüksek Lisans
ANADOLU ÜNİVERSİTESİ
SAĞLIK BİLİMLERİ ENSTİTÜSÜ
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2006 - 2010 Lisans
ESKİŞEHİR OSMANGAZİ ÜNİVERSİTESİ
FEN-EDEBİYAT FAKÜLTESİ
Araştırma Alanları
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Sağlık Bilimleri Temel Alanı
Farmakoloji
Mesleki Deneyim
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2019 - ÖĞRETİM GÖREVLİSİ
PAMUKKALE ÜNİVERSİTESİ TAVAS SAĞLIK HİZMETLERİ MESLEK YÜKSEKOKULU ECZANE HİZMETLERİ BÖLÜMÜ
ECZANE HİZMETLERİ PR.
İdari Görevler
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MYO/Yüksekokul Müdür Yardımcısı
Yurt İçi
PAMUKKALE ÜNİVERSİTESİ
Yayınlar ve Eserler
Makaleler
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Enhanced angiogenesis of human umbilical vein endothelial cells via THP‐1‐derived M2c‐like macrophages and treatment with proteasome inhibitors ‘bortezomib and ixazomib’
APMIS
Özgün Makale Uluslararası
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Anticarcinogenic activity of Cl-Amidine on non-small cell lung cancer
Journal of Experimental and Clinical Medicine
Özgün Makale Uluslararası
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The investigation of cytotoxic and apoptotic activity of Cl-amidine on the human U-87 MG glioma cell line
Medicine
Özgün Makale Uluslararası
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Pro-inflammatory ‘M1 macrophage’ vs anti-inflammatory ‘Hydrocortisone’ a new approach to wound healing in HaCaT cells
İstanbul Journal of Pharmacy
Özgün Makale Uluslararası
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Investigation of the Effectiveness of Cl-Amidine on Wound Healing: An In Vitro Study
Mid Blac Sea J Health Sci
Özgün Makale Uluslararası
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Comparative Analysis of Antioxidant and Anticancer Activities of Fruiting bodies, Mycelial Biomass and Culture Liquid of Omphalotus olearius OBCC 2503 (Agaricomycetes) from Turkey
International Journal of Medicinal Mushrooms
Özgün Makale Uluslararası
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Proteasome inhibitor immunotherapy for the epithelial to mesenchymal transition: assessing the A549 lung cancer cell microenvironment and the role of M1, M2a and M2c \u2018hydrocortisone-polarised\u2019 macrophages
Molecular Biology Reports
Özgün Makale Uluslararası
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Comparison of the apoptotic effects of bortezomib using 2D and 3D co-culture models of THP-1 derived macrophage and A549 lung cancer
Journal of Research in Pharmacy
Özgün Makale Uluslararası
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Investigation of the neuroprotective and neuritogenic effects of halotolerant Penicillium flavigenum-derived sorbicillin-like compounds on PC-12 Adh cells
Cytotechnology
Özgün Makale Uluslararası
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Therapeutic Potentials of İnhibition Jumonji C Domain Containing Demethylases in Acute Myeloid Leukemia
Turkish Journal of Hematology
Özgün Makale Uluslararası
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Gallic Acid Reduces Experimental Colitis in Rats by Downregulation of Cathepsin and Oxidative Stress
Erciyes Medical Journal
Özgün Makale Uluslararası
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Anticancer and antimetastatic activity of Hypomyces chrysospermus, a cosmopolitan parasite in different human cancer cells
Molecular Biology Reports
Özgün Makale Uluslararası
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Gallic Acid Reduces Experimental Colitis in Rats by Downregulation of Cathepsin and Oxidative Stress
Erciyes Medical Journal
Özgün Makale Uluslararası
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Synthesis and Anticancer Activity of New Hydrazide-hydrazones and Their Pd(II) Complexes
Letters in Drug Design Discovery
Özgün Makale Uluslararası
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Effect of Silymarin on Cathepsin Activity and Oxidative Stress in TNBS-induced Colitis in Rats
Asian Journal of Biochemistry, Genetics and Molecular Biology
Özgün Makale Uluslararası
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Inhibitory effects of secondary metabolites of halotolerant Aspergillus terreus on angiogenesis.
BIOMEDICAL RESEARCH-INDIA
Özgün Makale Uluslararası
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Evaluation of Antiangiogenic and Antimetastatic Effects of Penicillium chrysogenum Secondary Metabolites
Indian Journal of Pharmaceutical Sciences
Özgün Makale Uluslararası
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NEURITOGENIC ACTIVITY OF EPIGALLOCATECHIN GALLATE AND CURCUMIN COMBINATION ON RAT ADRENAL PHEOCHROMOCYTOMA CELLS
FRESENIUS ENVIRONMENTAL BULLETIN
Özgün Makale Uluslararası
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The evaluation of the anti-cancer activity of ixazomib on Caco2 colon solid tumor cells, comparison with bortezomib
Acta Clinica Belgica
Özgün Makale Uluslararası
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Synthesis and antiproliferative activity evaluation of new thiazole-benzimidazole derivatives using real-time cell analysis (RTCA DP)
MEDICINAL CHEMISTRY RESEARCH
Özgün Makale Uluslararası
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Comparison of antiproliferative and apoptotic effects of a novel proteasome inhibitor MLN2238 with bortezomib on K562 chronic myeloid leukemia cells
Immunopharmacology and Immunotoxicology
Özgün Makale Uluslararası
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The hepatoprotective effects of Hypericum perforatum L. on hepatic ischemia/reperfusion injury in rats
Cytotechnology
Özgün Makale Uluslararası
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Antiangiogenic and antiproliferative effects of halotolerant Penicillium chrysogenum var. chrysogenum on the human umbilical vein endothelial cells (HUVECs)
2013 E-HEALTH AND BIOENGINEERING CONFERENCE (EHB)
Özgün Makale Uluslararası
Bildiriler
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Evaluation of the Effects of Anti/Pro Inflammatory Cytokines on THP-1 Derived Macrophage Proliferation with Real-Time Cell Analyzer
1st International Conference on Innovative Academic Studies (ICIAS)
Tam metin bildiri Uluslararası
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A New Perspective on Proteasome Inhibitors: A549 Lung Cancer Cell Microenvironment with M1 Polarized Macrophages
International Conferences on Science and Technology, Natural Science and Technology
Tam metin bildiri Uluslararası
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Potentiation of the neuritogenic effects of PC-12 Adh Cells with Trichostatin A and RG108 combination
International Eurasian Conference on Biotechnology and Biochemistry (BioTechBioChem 2020)
Özet bildiri Uluslararası
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The effects on neuronal differentiation of Trichostatin-A and RG108 combinations using Real Time Cell Analysis
International Eurasian Conference on Biotechnology and Biochemistry (BioTechBioChem 2020)
Özet bildiri Uluslararası
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Optimization of THP-1 Monocyte / Macrophage Polarization Using PMA
International Eurasian Conference on Biotechnology and Biochemistry (BioTechBioChem 2020)
Tam metin bildiri Uluslararası
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Effects of Sorbicillin-like Secondary Metabolite on 6-OHDA-Induced in vitro Parkinson’s Disease Model
4th INTERNATIONAL CONGRESS ON APPLIED BIOLOGICAL SCIENCES (ICABS)
Özet bildiri Uluslararası
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Sweetgum Oil (Liquidambar orientalis) Promotes Migration and Proliferation of HaCaT Human Keratinocytes Cells
4th INTERNATIONAL CONGRESS ON APPLIED BIOLOGICAL SCIENCES (ICABS)
Özet bildiri Uluslararası
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Optimization of Spheroid Growth in AlgiMatrix 3D Culture System
4th INTERNATIONAL CONGRESS ON APPLIED BIOLOGICAL SCIENCES (ICABS)
Özet bildiri Uluslararası
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Effects of Histone Deacetylase Inhibitor Trichostatin A and DNA Methyltransferase Inhibitor RG108 Combination on THP-1 Monocyte Cells’ Cytokine Levels
IVEK 3rd International Convention of Pharmaceuticals and Pharmacies
Özet bildiri Uluslararası
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Effects of Epigenetic Mechanisms Related Compounds On Neurotrophin Signaling Pathway
IVEK 3rd International Convention of Pharmaceuticals and Pharmacies
Özet bildiri Uluslararası
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Investigation of the Effectiveness of Cl-Amidine on Wound Healing: An In Vitro Study
IVEK 3rd International Convention of Pharmaceuticals and Pharmacies
Özet bildiri Uluslararası
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Pro/Anti inflammatory Potency of Aspergillus Terreus Secondary Metabolites on Human THP-1 Monocytes
IVEK 3rd International Convention of Pharmaceuticals and Pharmacies
Özet bildiri Uluslararası
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Investigation of Pro/Anti Inflammatory Effects of Ethylacetate Extracts of Penicillium Sp. on Human THP-1 Monocyte Cells
IVEK 3rd International Convention of Pharmaceuticals and Pharmacies
Özet bildiri Uluslararası
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Induction of Neurite Outgrowth Associated Bcl-2 Gene Expression Levels by Epigenetic Mechanisms Related Compounds
IVEK 3rd International Convention of Pharmaceuticals and Pharmacies
Özet bildiri Uluslararası
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Antiproliferative and Antimetastatic Effects of Miconazole on Human Non-Small Lung and Colon Cancer Cells
Basel Life Science Week MipTec Exhibition
Özet bildiri Uluslararası
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Real-Time Monitoring of the Antiproliferative and Antimetastatic Effects of Clotrimazole on A549 and Caco-2 Cells
Basel Life Science Week MipTec Exhibition
Özet bildiri Uluslararası
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Cell Proliferative and Neuritogenic Effects of Trichostatin A and RG108 Combination On NGF-Induced Neurite Outgrowth of PC-12 Adh Cells
Basel Life Science Week MipTec Exhibition
Özet bildiri Uluslararası
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Investigation of Anticancer Effects of Exopolysaccharides Isolated from Pleurotus ostreatus on Colon and Lung Cancer Cell Lines
Basel Life Science Week MipTec 2016
Özet bildiri Uluslararası
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Investigation of the Effects of Pleurotus ostreatus an Edible Mushroom on PC 12 Adh Cell Differentiation
Basel Life Science Week MipTec 2016
Özet bildiri Uluslararası
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Neuritogenic Potential of DNMT and HDAC Inhibitors RG108 and Trichostatin A Combination on NGF induced Neurite Outgrowth of PC 12 Adh Cells
Basel Life Science Week MipTec 2016
Özet bildiri Uluslararası
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Investigation of Antiproliferative and Apoptotic Effects of Tioconazole on Caco 2 Cell Line
Basel Life Science Week MipTec 2016
Özet bildiri Uluslararası
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Investigation of Antiproliferative Effects of Salicylanilide on Caco 2 A549 and MCF7 Cell Lines
Basel Life Science Week MipTec 2016
Özet bildiri Uluslararası
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Küçük hücreli olmayan akciğer kanserinde Cl amidin in antikanserojenik etkinliği
Uluslararası Katılımlı XIII. Ulusal Histoloji ve Embriyoloji Kongresi
Özet bildiri Uluslararası
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İnsan U-87 MG glioma hücre hattı üzerine Cl-amidin’in sitotoksik ve apoptotik etkinliğinin araştırılması
14. ULUSAL SİNİRBİLİM KONGRESİ
Özet bildiri Ulusal
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Bortezomib ve Metilstatın Farklı Multipl Myeloma Hücre Hatları Üzerindeki Sinerjik Apoptotik Etkileri
II. ULUSLARARASI KATILIMLI DENEYSEL HEMATOLOJİ KONGRESİ
Özet bildiri Uluslararası
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Diabetic Nephropaty Susceptibility and Pharmacogenetic Approaches
1st Pharmacogenomıcs İstanbul Summit,Increasing The Safety And Effectiveness of Personalized Therapy for Metabolic Disorders
Özet bildiri Uluslararası
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Effects of an Epigenetic Drug, A Histon Deacetylase İnhibitor, on Neurite Outgrowth of PC-12 Adh Cell Line
1st Pharmacogenomıcs İstanbul Summit,Increasing The Safety And Effectiveness of Personalized Therapy for Metabolic Disorders
Özet bildiri Uluslararası
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Affymetrix Primeview Array Analysis of Neurokinin-1 Receptor Antagonist Aprepitant on Glioblastoma Cells
1st Pharmacogenomıcs İstanbul Summit,Increasing The Safety And Effectiveness of Personalized Therapy for Metabolic Disorders
Özet bildiri Uluslararası
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Effects of a Novel DNA Methlytransferase Inhibitor (RG108), on a Neurite OutGrowth Marker GAP-43 mRNA Expression Levels
1st Pharmacogenomıcs İstanbul Summit,Increasing The Safety And Effectiveness of Personalized Therapy for Metabolic Disorders
Özet bildiri Uluslararası
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Diabetic Retinopathy and Associated Gene Polymorphisms
1st Pharmacogenomıcs İstanbul Summit,Increasing The Safety And Effectiveness of Personalized Therapy for Metabolic Disorders
Özet bildiri Uluslararası
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Investigation of The Effects of 5-Fluorocytosine on Cytokine Levels of Human Monocytes
1st Pharmacogenomıcs İstanbul Summit, Increasing The Safety And Effectiveness of Personalized Therapy for Metabolic Disorders
Özet bildiri Uluslararası
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Antiangiogenic and Antiproliferative Potency Of Aspergillus Sp. Secondary Metabolites On Human Umbilical Vein Endothelial Cells (Huvecs)
International Multidisciplinary Symposium On Drug Research Development,
Özet bildiri Uluslararası
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Effect On The Cytokine Pathway Related Genes Of NK-1 Receptor Antagonıst Aprepıtant in U87MG Glioblastoma Cells
Internatıonal Multıdıscıplınary Symposium On Drug Research Development
Özet bildiri Uluslararası
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Effects of Aprepitant, NK-1 Receptor Antagonist, On Mmp -2,-9 And Il -6, -8 Levels in Human Glioblastoma Cell Line
Internatıonal Multıdıscıplınary Symposium On Drug Research Development
Özet bildiri Uluslararası
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Antimetastatic Potential Of Aprepitant on Human Glioblastoma Cell Line
International Multidisciplinary Symposium On Drug Research Development,
Özet bildiri Uluslararası
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Investigation of Anti-Candidal Effect of Halotolerant Fungal Secondary Metabolites
International Work-Conference on Bioinformatics and Biomedical Engineering
Özet bildiri Uluslararası
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A DNA Methyltransferase Inhibitor RG108 Potentiates NGF-Induced Neurite Outgrowth of PC-12 Adh Cells
International Work-Conference on Bioinformatics and Biomedical Engineering
Tam metin bildiri Uluslararası
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Comparison of the Cytotoxic Effects of RG108 (A DNA Methyltransferase Inhibitor) Alone and Combination With Nerve Growth Factor on PC-12 Adh Cells
International Work-Conference on Bioinformatics and Biomedical Engineering
Özet bildiri Uluslararası
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Determination of Anti-Proliferative Effects of Secondary Metabolites Isolated from Halotolerant Fungi, on Colon Cancer Cells by Real Time Cell Analyze System (Xcellinge)
International Work-Conference on Bioinformatics and Biomedical Engineering
Özet bildiri Uluslararası
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Comparison of In Vitro Anticarcinogenic Effects of Proteasome Inhibitor MLN9708 and Bortezomib on Caco2 Cells,
2. International BAU Drug Design Congress
Özet bildiri Uluslararası
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Evaluation of the wound healing potentials of three Achillea species on cultured NIH3T3 fibroblasts
2nd International Conference and Exhibition on Pharmacognosy, Phytochemistry Natural Products
Özet bildiri Uluslararası
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Cytotoxıc And Antıprolıferatıve Effects Of Secondary Metabolıtes Of Halotolerant Penıcıllıum Sp. On Colon Adenocarcınoma (Caco-2) Cells Usıng Xcellıgence Technology
Drug Discovery and Therapy World Congress
Özet bildiri Uluslararası
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NF-κB Plays An Important Role in Proteasome Inhibition of MLN9708 On Caco2 Human Colon Cancer Cell Line
Drug Discovery and Therapy World Congress
Özet bildiri Uluslararası
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The cytotoxıc effects of Griseofulvın on colon adenocarcınoma cell line (Caco-2) using MTT assay and Xcellıgence technology.
1st International Congress on Controversies in Personalized Oncology (CONPO) Breast, Colon, Lung and Melanoma,
Özet bildiri Uluslararası
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Cytotoxıc and apoptotic effects of MLN9708, a new proteasome inhibitor, in human colon cancer Caco2 cell line.
1st International Congress on Controversies in Personalized Oncology (CONPO) Breast, Colon, Lung and Melanoma
Özet bildiri Uluslararası
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Antiangiogenic and antiproliferative effects of halotolerant Penicillium chrysogenum var. chrysogenum on the human umbilical vein endothelial cells (HUVECs)
The 4th IEEE International Conference on E-Health and Bioengineering - EHB
Özet bildiri Uluslararası
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Cytotoxic effect of angiogenesis inhibitor Fumagillin on C6 glioma cells
2nd International Congres on Neurobiology, Psychopharmacology and Treatment Guidance, Thessaloniki Greece
Tam metin bildiri Uluslararası
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The Protective Effect Of Hypericum Perforatum in experimental Renal Ischemia/Reperfusion Injury in The Rats
The 17th Congress of the International Federation of Associations of Anatomists (IFAA)
Özet bildiri Uluslararası
Kitap / Kitap Bölüm
Projeler ve Patentler
Projeler
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1 Proteazom İnhibitörleri Bortezomib Ve İxazomib'In M2c Polarize Makrofaj Ile Oluşturulan A549 Akciğer Kanseri Ko-Kültür Modelinde Metastaz/Inflamasyon Birlikteliğinin Araştırılması
Yürütücü -Tübitak 1002
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2 Sığala yağının hücre kültüründe yara iyileştici etkileri
Araştırmacı Yükseköğretim Kurumları tarafından destekli bilimsel araştırma projesi
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3 THP-1 Kökenli Makrofaj ve A549 Akciğer Kanseri 2D ve 3D Ko-Kültür Modelleri Kullanılarak Bortezomibin Apoptotik Etkilerinin Karşılaştırılması
Araştırmacı Yükseköğretim Kurumları tarafından destekli bilimsel araştırma projesi
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4 Halotolerant Penicillium Flavigenum’a Ait Sorbisillin Benzeri Bileşiklerin PC-12 Adh Hücrelerinde Nöroprotektif ve Nöritojenik Etkilerinin Araştırılması
Bursiyer -Tübitak 3001
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5 Aspergillus terreus ve Penicillium chrysogenum Sekonder Metabolitlerinin Antiinflamatuar Etkilerinin Araştırılması
Araştırmacı Yükseköğretim Kurumları tarafından destekli bilimsel araştırma projesi
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6 DNA Metiltransferaz İnhibitörü RG108 in Nörit Gelişimi Üzerine Etki Mekanizmalarının Araştırılması
Araştırmacı Yükseköğretim Kurumları tarafından destekli bilimsel araştırma projesi
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7 1409S385 - “Bazı Yeni 2-[4-(Sübstitüemetil)fenil]propiyonik Asit Türevlerinin Sentezlenmesi ve Biyolojik Etkilerinin Araştırılması” (Anadolu Üniversitesi AUBAP-Genel Amaçlı Proje)
Araştırmacı Yükseköğretim Kurumları tarafından destekli bilimsel araştırma projesi
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8 Makrofungus Hücre ve Sekonder Metabolitlerinin Antioksidan ve Antikanser Aktiviteleri
Bursiyer -Tübitak 1001
Sanatsal Faaliyetler
Ödüller
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Prof. Dr. M. L. Khorana IJPS Best Paper Award 2017
Yurtdışı kurum veya kuruluşlardan alınan bilim ödülü
Diğer Indian Pharmaceutical Association
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Best Poster Presentation Award (En iyi Poster Sunum Ödülü)
Yurtiçi kurum ve kuruluşlarından alınan bilim ödülü
Diğer SOCIETY FOR PHARMACOGENOMICS AND PERSONALIZED THERAPY